| Catalog Number | CI-460-33 |
| Product Id | CI-460-33 |
| Product Name | Interleukin-6 human (IL-6) (RECOMBINANT) |
| Temperature | -80°C |
| Unit | 25µg |
| Price | 250 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Growth Factors/Cytokines/Enzymes |
| Description | Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6. Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography. |
| Isotype | N/A |
| Mol Weight | 20-21 KDa (glycoprotein) |
| Purity | Over 85% pure by SDS gel electrophoresis. There is < 1ng/mg endotoxin. |
| Storage | Store at -80°C. |
| Stability | At least 1 year at -80°C. |
| Biological Activity | 3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent. |
| Formulation | Frozen liquid solution (PBS) at 0.50 mg/ml (50 µl/vial) |
| References | 1. Taga, T., and Kishimoto, T., (1997) Ann. Rev. Immunology, 15, 797-819 |
