| Catalog Number | TM-1701Y-55 |
| Product Id | TM-1701Y-55 |
| Product Name | Anti-human Elongator Protein 1 (ELP1) IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 150µg |
| Price | 425 |
| Availability | Available |
| Category | Proteins and Antibodies for Transcription Research |
| Subcategory | Proteins and Antibodies |
| Description | IgG fraction from mouse monoclonal antibody (clone 7E8/G10) obtained by immunization of mice with the largest subunit of Elongator complex (130 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG2a |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in ELISA assays (1: 1,000 dilution). It recognizes ELP1, the largest subunit of Elongator complex. Its function is not clear, but it has been demonstrated that the human Elongator facilitates transcription by RNA polymerase II in a chromatin- and acetyl-CoA-dependent manner. |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | Kim, J-H. (2002) Proc. Natl. Acad. Sci. USA 99, 1241 – 1246; Hawkes, N. et al. (2002) J. Biol. Chem. 277, 3047 – 3052. |
