| Catalog Number | MR-851-7 |
| Product Id | MR-851-7 |
| Product Name | Anti-human Vascular Endothelial Growth Factor receptor 1 (VEGFR-1 or FLT-1) IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 250µg |
| Price | 400 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Growth Factors/Cytokines/Receptors) |
| Description | IgG fraction from mouse monoclonal antibody (clone 6D1/G11) obtained by immunization of mice with the extracellular domain of human VEGFR-1 (106 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in ELISA assays (1: 8,000 dilution). It recognizes the extracellular domain of human VEGFR-1, a type I membrane protein. This protein binds VEGF, PLGF and VEGFB and belongs to the tyrosine protein kinase family. The VEGFR-1 has a signaling role in mediating monocyte chemotaxis in tumor disease and performs an inhibitory role by sequestering VEGF and preventing its interaction with VEGFR-2 |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | Ferrara, N. et. al. (2003) Nat. Med. 9, 669 – 676; Cross, M.J. et. al. (2003) Trends Biochem. Sci. 28, 488 – 494. |
