| Catalog Number | MA-MHC1-5 |
| Product Id | MA-MHC1-5 |
| Product Name | Anti-human MHC Class I IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 100µg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 1A6/C2) obtained by immunization of mice with human tonsil leukocyte membrane preparation. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG2a |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in ELISA, flow cytometry, immunohistochemistry (frozen sections) and Western blot analysis. It recognizes Major Histocompatibility Complex class I (MHC, human leukocyte antigen) MHC class I is a dimmer composed of two polypeptide chains, an a chain (44 kDa) and a non-covalently associated protein, b2 microglobulin (12 kDa). The antibody reacts with a monomorphic epitope on the a chain polypeptide of human class I HLA molecules (HLA-A,B,C). |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Paulsson, K.M. (2004) Cell. Mol. Life. Sci. 61, 2446 –2460; Shields, M.J. & Ribaudo, R.K. (1998) Tissue Antigens 51, 567-570; Bjorkman, P.J. et. al. (1987) Nature 329, 506 – 512. |
