| Catalog Number | MA-4031-5 |
| Product Id | MA-4031-5 |
| Product Name | Anti-human Class II Transactivator (Ciita) IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 100µg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 7D3/A1) obtained by immunization of mice with recombinant human CIITA fusion protein. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in ELISA, Western Blot, and immunoprecipitation. It recognizes CIITA, a non-DNA binding coactivator considered as the master regulator of basal and induced MHC class II specific gene expression. CIITA ensures a tight transcriptional control of these antigen-presenting genes to meet with local requirements for an adequate immune response. |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | LeibundGut-Landmann, S. et. al. (2004) Eur. J. Immunol. 34, 1513 – 1525; Van den Elsen, P. et. al. (2004) Curr. Opin. Immunol. 16, 67 – 75 ; Naves, R. et. al. (2002) Int. Immunol. 14, 481 – 491. |
