| Catalog Number | MA-404-5 |
| Product Id | MA-404-5 |
| Product Name | Anti-human b-2-Microglobulin IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 100µg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 3G8/B2) obtained by immunization of mice with human EBB-B cell line. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in ELISA and flow cytometry studies. It recognizes b-2-microglobulin, a cell membrane protein (12 kDa) non-covalent associated to MHC class I molecules. b-2-microglobulin associates with the a3 subdomain of the a heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class I molecules |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Paulsson, K.M. (2004) Cell. Mol. Life. Sci. 61, 2446 – 2460; Pamer, E. & Cresswell, P. (1998) Ann. Rev. Immunol. 16, 323 – 358; Solheim, J.C. (1999) Immunol. Rev. 172, 11 – 19. |
