Catalog Number | MA-CD21-6 |
Product Id | MA-CD21-6 |
Product Name | Anti-human Complement Receptor 2 (CR2 or CD21) IgG fraction (monoclonal) |
Temperature | -20°C |
Unit | 200µg |
Price | 275 |
Availability | Available |
Category | Growth Factors, Cytokines, Receptors and their Antibodies |
Subcategory | Monoclonal Antibodies (Immunology Antigens) |
Description | IgG fraction from mouse monoclonal antibody (clone 8B5/H5) obtained by immunization of mice with a human B cell line. The IgG fraction was purified using Protein G-Sepharose. |
Isotype | IgG2a |
Purity | N/A |
Storage | Store at -20°C. |
Stability | Stable for at least one year. Avoid repeated freezing and thawing |
Biological Activity | This antibody can be used in ELISA assays. It recognizes human CD21 (CR2), a 145 kDa type I integral membrane glycoprotein. CD21 is a receptor for the C3d complement fragment and for the Epstein-Barr virus, expressed on mature B cells, follicular dendritic cells, and some epithelial cells. It plays a role in B cell activation and proliferation. |
Formulation | Solution at 1.0 mg/mL in PBS |
References | Carroll, M.C. (2004) Mol. Immunol. 41, 141 – 146; Hannan, J. et. al. (2002) Biochem. Soc. Trans. 30, 983 – 989; Weis, J.J. et al. (1984) Proc. Natl. Acad. Sci. USA, 81, 881 – 885. |