| Catalog Number | MA-CD11A-6 |
| Product Id | MA-CD11A-6 |
| Product Name | Anti-human Lymphocyte Function Associated antigen (LFA-1) alpha Chain; CD11A; Integrin alpha L IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 200µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 1F1/A2) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in immunoprecipitation, and flow cytometry. It also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD11a (also known as integrin aL, or LFA-1 a chain), a type I membrane protein (180 kDa) expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. CD11a binds intracellular adhesion molecules (ICAMs), mediates cell adhesion and cytoskeletal organization and plays a role in most immune/inflammatory responses. |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Pribila, J.T. et. al. (2004) Ann. Rev. Immunol. 22, 157 |
