| Catalog Number | MA-CD2-6 |
| Product Id | MA-CD2-6 |
| Product Name | Anti-human Lymphocyte Function Associated antigen 2 (LFA-2); CD2; (E-Rosette Receptor) IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 200µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 8A2/H11) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in immunoprecipitation, and flow cytometry. It also inhibits the cytolic T lymphocyte (CTL) activity. It recognizes CD2 (also known as LFA-2, or E-rosette receptor), a 50 kDa transmembrane glycoprotein expressed on T cells, NK cells, cortical thymocytes and most malignant cells of T cell origin. It binds CD58 (LFA-3) to mediate cell adhesion and it is also receptor for CD59, and CD48. CD2 plays a critical role in activation of T cells. |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | van der Merwe, P. A. & Davis S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684 ; Hahn, W. et. al. (1992) Science, 256, 1805 – 1807 ; Moingeon, P. et. al. (1989) Immunol. Rev. 111, 111 – 144. |
