| Catalog Number | MA-CD58-6 |
| Product Id | MA-CD58-6 |
| Product Name | Anti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 200µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 2B2/D3) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Purity | N/A |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing |
| Biological Activity | This antibody can be used in immunoprecipitation, and flow cytometry, it also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD58 (also known as LFA-3), a 60-70 kDa membrane glycoprotein member of the immunoglobulin super family. CD58 is expressed on haemopoetic cells and it functions as an adhesion molecule mediating a co-stimulatory signal through CD2. |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | van der Merwe, P.A. & Davis, S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684; Wang, J-H. et. al. (1999) Cell 97, 791 – 803; Wallner, B.P. et. al. (1987) J. Exp. Med. 166, 923 – 932. |
