| Catalog Number | PCA-3000a-9 |
| Product Id | PCA-3000a-9 |
| Product Name | Rabbit anti-Human p53-associated Parkin-like Cytoplasmic Protein (PARC) IgG fraction polyclonal antibody |
| Temperature | -20°C |
| Unit | 1mg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Polyclonal Antibodies (Cancer/Apoptosis) |
| Description | IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (FFFGDEEEDEDEAYD) corresponding to amino acids 2503-2517 of human PARC. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | N/A |
| Mol Weight | N/A |
| Purity | N/A |
| Storage | Store at -20ºC. |
| Stability | Stable at least one year at -20ºC. Avoid repeated freezing and thawing. |
| Biological Activity | This polyclonal antibody reacts in ELISA (1: 250 dilution) and Western blot (1: 1,000 dilution) using the immunizing peptide. P53-associated parkin-like cytoplasmic protein (PARC) is a 270 kDa protein that acts as a cytoplasmic anchor for p53 unstressed cells, thereby regulating the localization and subsequent function of p53. It contains a cullin domain and a RING-IBR-RING domain at the carboxy terminus and it is ubiquitously expressed. |
| Formulation | Solution at 0.5 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial. |
| References | Nikolaev, A.Y. et al. (2003) Cell 112, 29-40. Nikolaev, A.Y. & Gu, W. (2003) Cell Cycle 2, 169-171. |
