| Catalog Number | PN-7000b-9 |
| Product Id | PN-7000b-9 |
| Product Name | Rabbit anti-Human Alpha- Synuclein IgG fraction polyclonal antibody |
| Temperature | -20°C |
| Unit | 1mg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Polyclonal Antibodies (Neurobiology) |
| Description | IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (MPVDPDNEAYEMPSEE) corresponding to amino acids 116 - 131 of human Alpha-Synuclein. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | N/A |
| Mol Weight | N/A |
| Purity | N/A |
| Storage | Store at -20ºC. |
| Stability | Stable at least one year at -20ºC. Avoid repeated freezing and thawing. |
| Biological Activity | This polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. Human Alpha Synuclein is a soluble protein highly abundant in presynaptic nerve terminals and a member of the synuclein family. It can form filamentous aggregates that are the major non-amyloid components of intracellular inclusions in several neurodegenerative diseases such as Alzheimer and Parkinson. |
| Formulation | Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial. |
| References | Clayton, D.F. & George, J.M. (1998) Trends Neurosci. 21 (6), 249 254. Goldberg, M.S. & Lansbury Jr., P.T. (2000) Nat. Cell Biol. 2, 115 - 119. George, J.M. (2002) Genome Biol.3, 3002.1 - 3002.6. Alves da Costa, C. (2003) Curr. Mol. Med. 3, 17 - 24. |
