| Catalog Number | PN-7030a-9 |
| Product Id | PN-7030a-9 |
| Product Name | Rabbit anti-Human Alpha, Beta and Gamma- Synuclein IgG fraction polyclonal antibody |
| Temperature | -20°C |
| Unit | 1mg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Polyclonal Antibodies (Neurobiology) |
| Description | IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (AKEGVVAAEKTKQGV) corresponding to amino acids 11 - 26 of human alpha, beta and gamma-synuclein. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | N/A |
| Mol Weight | N/A |
| Purity | N/A |
| Storage | Store at -20ºC. |
| Stability | Stable at least one year at -20ºC. Avoid repeated freezing and thawing. |
| Biological Activity | This polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. The synucleins (alpha, beta and gamma) are a family of soluble presynaptic proteins expressed in neural tissue. Synucleins are thought to be involved in neuronal plasticity, synaptic function, and neurodegenerative diseases. Gamma-synuclein is abnormally expressed in tumor tissues of different cancers. |
| Formulation | Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial. |
| References | Clayton, D.F. & George, J.M. (1998) Trends Neurosci. 21 (6), 249 254. Lavedan, C. (1998) Genome Res. 8, 871 - 880. George, J.M.(2002) Genome Biol.3, 3002.1 - 3002.6 |
