| Catalog Number | MI-300-3 |
| Product Id | MI-300-3 |
| Product Name | Human recombinant MIP-1 beta |
| Temperature | -80°C |
| Unit | 10µg |
| Price | 200 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Macrophage Inflammatory Proteins |
| Description | Macrophage Inflammatory Protein MIP-1 beta is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1 beta affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1 beta also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1 beta is composed of 69 amino acid residues with one possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1 beta is 60% homologous with human MIP-1 beta. Human recombinant MIP-1 beta is produced in genetically engineered yeast, and purified by sequential chromatography. |
| Isotype | N/A |
| Mol Weight | 8 KDa |
| Purity | Over 95% pure by SDS gel electrophoresis, with low level of endotoxin. |
| Storage | Store at -80°C. |
| Stability | Several months at -80°C. |
| Biological Activity | The biological activity of recombinant human MIP-1 alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis. |
| Formulation | In water at a concentration of 1.0 mg protein/ml |
| References | 1. Nathan, C.F. (1987)J. Clin. Invest. 79:319
2. Tekamp-Olson. P. et al. (1990) J. Exp. Med. 172:911
3. Wolpe S.D. et al. (1989) Proc. Natl. Acad. Sci. (USA) 86:612 |
