| Catalog Number | GF-050-4 |
| Product Id | GF-050-4 |
| Product Name | Insulin-like Growth Factor (IGF-I) human (RECOMBINANT) |
| Temperature | +4°C |
| Unit | 50µg |
| Price | 100 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Growth Factors/Cytokines/Enzymes |
| Description | Human IGF-I is a potent mitogen for mesenchymally-derived cells. It is composed of 70 amino acid residues, and is 62% homologous with human IGF-II. Human IGF-I is produced by genetically engineered yeast, and purified by sequential chromatography. |
| Isotype | N/A |
| Mol Weight | 7.5 KDa |
| Purity | Over 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis. |
| Storage | Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80°C is recommended. |
| Stability | Several months, lyophilized or in solution, at pH 6-7 and +4°C. |
| Biological Activity | The material is active in a receptor-binding assay using a membrane preparation from placenta. |
| Formulation | Lyophilized powder |
| References | 1. Modern Concepts of Insulin-Like Growth Factor. Ed. E. Martin Spencer, M.D. (1991). Elsevier Science Publ. (New York).
2 D'Ercole, A.J. (1987) J. Dev. Physiol. 9:481-495
3. Daughaday, W.H. and Rotwein, P. (1989) Endocr. Rev. 10:68-91 |
