| Catalog Number | TM-281-55 |
| Product Id | TM-281-55 |
| Product Name | Anti- human large subunit (68 kDa) of TFIIE-gamma IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 150µg |
| Price | 425 |
| Availability | Available |
| Category | Proteins and Antibodies for Transcription Research |
| Subcategory | Proteins and Antibodies |
| Description | IgG fraction from mouse monoclonal antibody (clone 4C2/E7) obtained by immunization using purified human transcription factor IIE-gamma (p68). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG2a |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA (1: 8000 dilution) and Western blot analysis. It recognizes the large subunit (68 kDa) of TFIIE-gamma complex. This complex recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. |
| Formulation | Solution at 1.0 mg/mL in PBS (pH 7.2). |
| References | Peterson, M.G. et al (1991) Nature 354, 369 – 373.
Kuhlman, T.C. et al (1999) Mol. Cell. Biol. 19, 2130 – 2141. |
