| Catalog Number | TM-541-55 |
| Product Id | TM-541-55 |
| Product Name | Anti-human Sirtuin type 7 (Sirt 7). IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 150µg |
| Price | 425 |
| Availability | Available |
| Category | Proteins and Antibodies for Transcription Research |
| Subcategory | Proteins and Antibodies |
| Description | IgG fraction from mouse monoclonal antibody (clone 3A9/H6) obtained by immunization of mice with an ovalbumin-conjugated synthetic peptide corresponding to N-terminal aa1 - aa50 of human silent information regulator 2 homolog (Sirt7). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA assay (1:8,000 dilution). It recognizes Sirt7, a NAD-dependent deacetylase, cytoplasmatic protein located under the nuclear membrane involved in diverse processes ranging from regulation of gene silencing to DNA damage response in mammalian cells. |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | Smith, J.S. et. al. (2002) Methods Enzymol. 353, 282 - 300.0
Frye, R. (2000) Biochem. Biophys. Res. Commun. 273, 793 - 798.
Frye, R. (1999) Biochem. Biophys. Res. Commun. 260, 273 - 279. |
