| Catalog Number | MR-951-4 |
| Product Id | MR-951-4 |
| Product Name | Anti-hTNF Receptor-Associated Factor 2 (TRAF 2). IgG faction (monoclonal) |
| Temperature | -20°C |
| Unit | 50µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Growth Factors/Cytokines/Receptors) |
| Description | IgG fraction from mouse monoclonal antibody (clone 2I10/I5) obtained by immunization of mice with human TRAF2 (50 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA assay (1:2,000 dilution). TRAF2 is a signal transducer protein that associates with the cytoplasmic domain of TNF receptor to different signaling pathways. It regulates two distinct kinase cascades which lead to NF-?B and JUNK activation. It is also involved in anti-apoptotic signaling, perinatal survival and IL-15 signaling. |
| Formulation | Solution at 1.0 mg/mL in PBS. |
| References | Chung, Y.J. et. al. (2002) J. Cell. Sci. 115, 679 - 688.
Bradley, J.R. & Pober, J. (2001) Oncogene 20, 6482 - 6491.
Wajant, H. et. al. (2001) Cell. Signal. 13, 389 - 400. |
