| Catalog Number | MR-961-4 |
| Product Id | MR-961-4 |
| Product Name | Anti-hTNF Receptor-Associated Factor 3 (TRAF 3). IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 50µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Growth Factors/Cytokines/Receptors) |
| Description | IgG fraction from mouse monoclonal antibody (clone 5F8/G1) obtained by immunization of mice with human TRAF3 (60 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG2a |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA assay (1:2,000 dilution). TRAF3 is a signal transducer protein that associates with the cytoplasmic domain of TNF receptor to different signaling pathways. It is important in T-cell dependent immune responses; it mediates signaling by CD40 and the lymphotoxin ß receptor. |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Chung, Y.J. et. al. (2002) J. Cell. Sci. 115, 679 - 688.
Bradley, J.R. & Pober, J. (2001) Oncogene 20, 6482 - 6491.
Wajant, H. et. al. (2001) Cell. Signal. 13, 389 - 400.
Marsters, S.A. et. al. (1997) J. Biol. Chem. 272, 14029 - 14032. |
