| Catalog Number | MA-1011a-5 |
| Product Id | MA-1011a-5 |
| Product Name | Anti-Tissue Factor Pathway Inhibitor (TFPI). IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 100µg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Growth Factors/Cytokines/Receptors) |
| Description | IgG fraction from mouse monoclonal antibody (clone 6F3/C12) obtained by immunization of mice with a truncated TFPI (34 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG2b |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA assay (1:2,000 dilution). TFPI is the main physiological inhibitor of the extrinsic coagulation pathway. It is a Kunitz-type serine protease inhibitor comprising three tandem units; the first and second units inhibit Factor VIIa/tissue factor complex and factor Xa respectively. |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Price, G.C. et. al. (2004) Anaesthesia 59, 483 - 492.
Johnson, K. et. al. (1998) Thromb. Haemost. 80, 585 - 587. |
