| Catalog Number | MR-421B-4 |
| Product Id | MR-421B-4 |
| Product Name | Anti-Interleukin-2 Receptor Beta chain (Il-2R) extracellular domain (CD122). IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 50µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Growth Factors/Cytokines/Receptors) |
| Description | IgG fraction from mouse monoclonal antibody (clone 6B9/F11) obtained by immunization of mice with the extra-cellular domain of interleukin 2 receptor beta chain (32 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA assay (1:2,000 dilution). The IL-2R beta chain (CD122) associates with CD25 (IL-2R a chain), and CD132 (? chain of IL-2, IL-4, IL-7, IL-9, IL-13, IL-15 receptors) to form the high-affinity IL-2 receptor. It is critical for mediating biological effects of IL-2 and IL-15 on T cells and NK cells. |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Minami, Y. et. al. (1993) Ann. Rev. Immunol. 11, 245 - 268 |
