| Catalog Number | MA-771-5 |
| Product Id | MA-771-5 |
| Product Name | Anti-mouse Cripto-1 Protein (CR-1). IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 100µg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Cancer Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 8B10/H8) obtained by immunization of mice with Cripto-1 protein from mouse (27 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Storage | Store at -20°C. |
| Stability | Stable for at least one year. Avoid repeated freezing and thawing. |
| Biological Activity | This antibody can be used for ELISA assay (1:8,000). It recognizes mouse Cripto protein. Cripto-1 is a signaling protein and member of the epidermal growth factor protein family. It plays an important role during early embryonic development. It has also a role in tumor development, induces cell proliferation, reduces apoptosis and increases cell migration. Cripto-1 is released or shed from expressing cells and may serve as marker gene in the early to mid-progressive stages of a variety carcinomas. |
| Formulation | Solution at 0.5 mg/mL in PBS |
| References | Strizzi, L. et. al. (2004) J. Cell. Physiol. 201, 266 - 276.
Adamson, E.D. et. al. (2002) J. Cell. Physiol. 190, 267 - 278.
Minchiotti, G. et. al. (2002) Gene 287, 33 - 37.
Persico, M.G. et. al. (2001) Biochim. Biophys. Acta 1552, 87 - 93
Salomon, D.S. et. al. (2000) Endocr. Relat. Cancer 7, 199 - 226. |
