| Catalog Number | MR-771-7 |
| Product Id | MR-771-7 |
| Product Name | Anti-mouse Cripto IgG fraction (monoclonal) |
| Temperature | -20°C |
| Unit | 250µg |
| Price | 400 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Cancer Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 3C7/H4) obtained by immunization of mice with Cripto receptor from mouse (25 kDa). The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG2a |
| Biological Activity | This antibody can be used for ELISA assay (1:8,000). It recognizes mouse Cripto receptor. This protein binds Cripto to specifically activate the tyrosine kinase c-Src which is required for cell proliferation and migration of epithelial cells. |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | Strizzi, L. et. al. (2004) J. Cell. Physiol. 201, 266 - 276.
Adamson, E.D. et. al. (2002) J. Cell. Physiol. 190, 267 - 278.
Minchiotti, G. et. al. (2002) Gene 287, 33 - 37.
Persico, M.G. et. al. (2001) Biochim. Biophys. Acta 1552, 87 - 93
Salomon, D.S. et. al. (2000) Endocr. Relat. Cancer 7, 199 - 226. |
