| Catalog Number | MA-4011-6 |
| Product Id | MA-4011-6 |
| Product Name | Anti-human Vascular Cell Adhesion Protein 1(VCAM-1 or CD106). IgG fraction (monoclonal) |
| Temperature | Select |
| Unit | 200µg |
| Price | 275 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Monoclonal Antibodies (Immunology Antigens) |
| Description | IgG fraction from mouse monoclonal antibody (clone 6G10/8) obtained by immunization of mice with human umbilical vein endothelial cells (HUVEC) activated with a TNF. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | IgG1 |
| Biological Activity | This antibody can be used for functional studies of cell adhesion molecules. VCAM-1 is the receptor for ß-1 integrin VL4 on leukocytes and mediates both adhesion and signal transduction. The VCAM1-VL4 interaction may play a patho-physiologic role both in immune responses and in leukocyte emigration to sites of inflammation. This interaction is important in the specific tumor destruction. |
| Formulation | Solution at 1.0 mg/mL in PBS |
| References | Jin, Z. et. al. (2004) Int. J. Cancer 111, 558 - 567.
Hession, C. et. al. (1991) J. Biol. Chem. 266, 6682 - 6685. |
