| Catalog Number | CI-420-3 |
| Product Id | CI-420-3 |
| Product Name | Interleukin-2 human (IL-2) (RECOMBINANT) |
| Temperature | +2°C to +8°C |
| Unit | 10µg |
| Price | 100 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Growth Factors/Cytokines/Enzymes |
| Description | Human Interleukin-2 (IL-2) is a lymphokine which biological effects include activation and proliferation of T cells, B cells, and other lymphokine activated killer cells. Human IL-2 is composed of 133 amino acids, including 3 cysteine residues, two of which are involved in a disulfide bond essential for biological activity. Human and murine IL-2 are 62% homologous, and human IL-2 has been found to be active on murine cell lines. Human Interleukin-2 (RECOMBINANT) is produced in genetically engineered Escherichia coli cells, and purified by sequential chromatography. |
| Isotype | N/A |
| Mol Weight | 15 KDa |
| Purity | Over 95% pure by SDS gel electrophoresis. |
| Storage | Store at +2°C to +8°C |
| Stability | Several months as formulated, at +2°C to +8°C. |
| Biological Activity | The biological activity is determined by a lymphocyte proliferation assay and each vial contains 160,000 IU (International units) |
| Formulation | Lyophilized in the presence of stabilizer (mannitol), low levels of SDS (preventing aggregation), and Sodium Phosphate. It can be reconstituted in water giving a pH between 7.2-7.8. There are no preservatives in this formulation. |
| References | 1. Gillis, S., Ferm, M.M., Ou, W., and Smith, K.A., The Journal of Immunology, (1978) Vol 120, No. 6, June, 2027-2032
2. Mosmann, T., Journal of Immunological Methods, (1983) Vol 65, 55-63 |
